Seattle Grace Hospital welcomes a new batch of interns, and five medical school friends graduate. They need to compete for the official position of physician with good performance. The man she had a one-night stand with in the bar the night before turned out to be neurosurgeon Derek Sherber, and the entanglement with him began; Christina attracted the attention of thoracic surgeon Preston Burke, and they also Arrogant and ambitious; George secretly loves Meredith; the beautiful Isobel immediately started rumors, and the one-year internship period was full of high-density stress and hormones...